November 4, 2024 - 🧬 [nGram] Your Weekly Business Development Insights (28th Oct - 3rd Nov): Novartis Scemblix® FDA Approval & AI in Drug Discovery


  1. Teva's TEV-'749 shows improved social functioning in schizophrenia patients in Phase 3 SOLARIS trial.
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  2. Exactech's Truliant 3D Tibial Implant receives FDA clearance for knee replacement surgery.
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  3. FELIQS' FLQ-101 receives FDA Fast Track for Retinopathy of Prematurity prevention.
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  4. Hypothyroidism market to grow by USD 789.8 million by 2028, driven by new drug approvals and AI advancements.
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  5. Cancer drugs Palbociclib and Ribociclib show potential in treating Hereditary Hemorrhagic Telangiectasia by targeting CDK6 protein.
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  6. Kewaunee Scientific acquires Nu Aire for $55 million, expanding laboratory furniture and technical product offerings.
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  7. Galecto acquires rights to BRM-1420 for Acute Myeloid Leukemia, focusing on oncology and liver diseases.
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  8. Aileron and Advancium sign exclusive option agreement for ALRN-6924 to treat Retinoblastoma.
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  9. Evogene partners with Google Cloud to enhance AI-driven small molecule design for drug development and agriculture.
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  10. FDA approves Novartis' Scemblix for newly diagnosed Chronic Myeloid Leukemia, showing superior efficacy and safety in Phase III trial.
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  11. Anavex's Blarcamesine shows significant efficacy in Phase IIb/III trial for Alzheimer's Disease, slowing clinical decline by 36.3%.
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  12. Verastem submits NDA for avutometinib and defactinib to FDA for recurrent KRAS mutant low-grade serous ovarian cancer.
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  13. Accenture partners with 1910 Genetics to enhance drug discovery using AI for biopharma companies.
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  14. Illumina unveils new NGS and proteomics technologies at ASHG, enhancing genomic insights and multiomics capabilities.
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  15. Eisai completes FDA submission for LEQEMBI subcutaneous dosing for early Alzheimer's Disease under Fast Track status.
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  16. Seer showcases deep proteomics enhancing genomic insights for Alzheimer's Disease and Lung Cancer at ASHG 2024.
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  17. Sutro Biopharma initiates trial for Luvelta in pediatric patients with CBF/GLIS Acute Myeloid Leukemia.
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  18. Genentech's Itovebi doubles progression-free survival in HR-positive advanced Breast Cancer, per NEJM Phase III study.
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  19. Memo Therapeutics completes Phase II trial enrollment for potravitug in BK Viremia among kidney transplant patients.
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  20. ALX Oncology's evorpacept shows promise in Phase 1b/2 trial for HER2-positive metastatic breast cancer.
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  21. Blue Earth Therapeutics secures $76.5M to advance PSMA-targeted radioligand therapies for Prostate Cancer.
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  22. Biogen and Neomorph partner to develop molecular glue degraders for Alzheimer's Disease and rare immunological conditions.
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  23. Corcept reports positive Phase 3 trial results for relacorilant in Cushing's Syndrome, boosting financial outlook.
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  24. Diadem's p53-specific antibody shows promise for early Alzheimer's Disease detection at CTAD 2024.
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  25. Senhwa Biosciences appoints Dr. Yiu-Lian Fong as Corporate Director to enhance oncology and rare disease drug development.
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