November 6, 2024 - 🧬 [nGram] Your Weekly Business Development Insights (30th Oct - 5th Nov): AI in Antibody Design, FDA Clearances & Alzheimer's Advances


  1. Nxera Pharma partners with Antiverse to design GPCR-targeted antibody therapeutics using generative AI.
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  2. SUPLEXA shows promise in retraining immune cells for advanced Colorectal Neoplasms and Renal Cell Carcinoma.
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  3. HuidaGene's CRISPR/Cas13 RNA-editing therapy HG202 receives FDA clearance for Macular Degeneration treatment.
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  4. ALX Oncology to present Phase 1b/2 trial results of evorpacept and zanidatamab in HER2-positive Breast Neoplasms at SABCS 2024.
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  5. SimBioSys receives second FDA clearance for TumorSight Viz, enhancing breast cancer surgery decision support.
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  6. SUPLEXA shows promise in retraining immune cells for advanced Colorectal Neoplasms and Renal Cell Carcinoma.
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  7. Wave Life Sciences advances obesity and cardiometabolic RNA programs, with clinical trials set for 2025.
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  8. Eisai completes FDA submission for LEQEMBI subcutaneous dosing for early Alzheimer's Disease under Fast Track status.
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  9. Foghorn Therapeutics doses first patient in Phase 1 trial for SMARCA4 mutated NSCLC with FHD-909.
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  10. IDEAYA Biosciences advances darovasertib trials and reports strong financials, targeting multiple Phase 1/2 expansions in 2024.
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  11. Syndax and Royalty Pharma secure $350M funding for Niktimvo, targeting chronic Graft-versus-Host Disease.
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  12. OmniActive acquires ENovate Biolife to enhance its portfolio of clinically proven health ingredients.
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  13. Damona Pharmaceuticals receives FDA clearance for Phase 1 trial of DPX-101 targeting cognitive deficits in Major Depressive Disorder.
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  14. RIBOMIC's Phase IIa trial shows umedaptanib pegol increases growth rate in Achondroplasia by up to 4.6 cm/year in children.
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  15. Teva's Phase 3 SOLARIS trial shows TEV-'749 improves social functioning in Schizophrenia without PDSS events.
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  16. Ring Therapeutics partners with A*STAR and SERI to advance gene therapy R&D in Singapore for Ophthalmology and Oncology.
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  17. Illumina reports Q3 2024 revenue of $1.1 billion, lowers annual revenue guidance by 3%.
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  18. Formosa Pharmaceuticals' APP13007 shows success in Phase 3 trial for post-cataract surgery inflammation and pain in China.
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  19. Biotia's AI-powered urine test receives NY State approval for diagnosing Urinary Tract Infections with high accuracy.
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  20. J INTS BIO launches AI alliance to enhance precision medicine in Lung Neoplasms treatment.
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  21. PHAXIAM Therapeutics receives FDA approval for Phase II study on phage therapy for Prosthetic Joint Infections.
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  22. Xpert Mpox receives WHO Emergency Use Listing for rapid Mpox diagnosis.
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  23. AI in pathology market projected to reach USD 169.8 million by 2029, driven by digital pathology advancements.
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  24. Diadem's p53-specific antibody shows promise for early Alzheimer's Disease detection at CTAD 2024.
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  25. Leal Therapeutics secures $45M to advance ALS and Schizophrenia therapies to clinical trials by 2025.
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