January 7, 2025 - 🧬 [nGram] Your Weekly Business Development Insights (31st Dec - 6th Jan): Amgen's Lung Cancer Treatment, Stryker's Acquisition, & FDA Approvals


  1. Stryker to acquire Inari Medical for $4.9 billion, enhancing its peripheral vascular disease portfolio.
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  2. Amgen's IMDYLLTRA® receives UK approval for third-line treatment of extensive-stage Small Cell Lung Cancer.
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  3. Qu Biologics' QBECO SSI shows promise in reducing liver fat, inflammation, and fibrosis in Metabolic Dysfunction-Associated Fatty Liver Disease.
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  4. Tempest's amezalpat receives FDA Orphan Drug Designation for Hepatocellular Carcinoma treatment.
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  5. FDA grants priority review for CUTX-101 NDA for Menkes Disease treatment, with action date set for June 30, 2025.
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  6. China approves first stem cell therapy for acute graft-versus-host disease and new HIV drug lenacapavir.
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  7. CAR-T cell therapy market expands with new FDA approvals and late-stage trials targeting cancer treatment.
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  8. DiaCarta's blood test reduces colonoscopy need by 33% in FIT-positive Colorectal Cancer screening.
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  9. Novo Holdings invests €90M in Orbis Medicines for oral macrocycle drug development.
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  10. Oculis' OCS-05 shows positive Phase 2 trial results for Acute Optic Neuritis, meeting safety and efficacy endpoints.
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  11. TEPOXX approved in Japan for Orthopoxvirus treatment, including Smallpox, marking a significant regulatory milestone.
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  12. Genetic testing identifies drug resistance in Candida auris, improving treatment for this multidrug-resistant fungus.
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  13. Care Access offers no-cost screenings in Aurora for cardiovascular and kidney health, focusing on lipoprotein(a) risk awareness.
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  14. BeiGene acquires global rights for DualityBio's antibody-drug conjugate developed with Nona Biosciences.
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  15. CathWorks completes enrollment for ALL-RISE trial, evaluating FFRangio in Coronary Artery Disease treatment.
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  16. CHOP develops ATLAS-seq to enhance T cell receptor identification for cancer immunotherapy.
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  17. FDA grants priority review to CUTX-101 for Menkes Disease, potential first approved treatment.
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  18. Orbis Medicines raises EUR 90M to develop oral macrocycle drugs, appoints Morten Graugaard as CEO.
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  19. MilliporeSigma acquires HUB Organoids to enhance drug development with advanced organoid technology.
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  20. Waud Capital acquires Mopec Group to enhance pathology solutions and drive growth in healthcare markets.
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  21. ACELYRIN to present Phase 2 data and Phase 3 design for lonigutamab in Thyroid Eye Disease.
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  22. WuXi Biologics partners with Candid Therapeutics on trispecific T-cell engager for autoimmune diseases.
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  23. FDA approved 50 new molecular entities in 2024, marking the sixth year with 50+ approvals since 1985.
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  24. Sterilization equipment market projected to reach $26.77 billion by 2031, driven by pharmaceutical and biotechnology demand.
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  25. Renovaro to acquire Predictive Oncology, enhancing AI-driven cancer diagnostics and drug discovery capabilities.
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