February 4, 2025 - 🧬 [nGram] Your Weekly Business Development Insights (28th Jan - 3rd Feb): FDA Approvals & Major Financing in Pharma


  1. OS Therapies acquires full IP rights to OST-HER2 and two cancer assets for $8M.
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  2. uniQure's AMT-162 gene therapy for SOD1-ALS advances to second cohort after positive safety review.
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  3. Atalanta Therapeutics secures $97M to advance RNAi therapies for KCNT1-related epilepsy and Huntington's Disease to clinical trials.
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  4. Anticoagulants market projected to reach $89.5 billion by 2033, driven by cardiovascular disease prevalence and drug innovations.
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  5. Galderma introduces guidelines for managing facial changes in patients undergoing medication-driven weight loss.
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  6. Takeda appoints Julie Kim as CEO, marking a significant leadership change in June 2026.
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  7. GH Research's GH001 shows significant efficacy in Phase 2b trial for Treatment-Resistant Depression with rapid symptom reduction.
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  8. China Jo-Jo Drugstores restructures to focus on wholesale, enhancing profitability and growth.
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  9. FDA approves SYMBRAVO for acute treatment of Migraine, offering rapid and sustained pain relief with a novel multi-mechanistic approach.
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  10. NICE approves exa-cel gene therapy for severe Sickle Cell Disease, offering potential cure under managed access in NHS England.
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  11. Alterity's ATH434 shows significant efficacy in Phase 2 trial for Multiple System Atrophy, slowing disease progression by up to 48%.
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  12. Augnito partners with Almoosa Health to integrate AI Scribe, enhancing clinical workflows in Saudi Arabia.
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  13. CD39-targeted therapies show promise in oncology and autoimmune diseases, with first approval expected by 2029.
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  14. Orion and Invenra partner to develop bispecific antibody cancer therapeutics using Invenra's B-Body® platform.
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  15. GLP-1 receptor agonists impair taste function, affecting dietary choices and metabolic health, study reveals.
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  16. BioAro's PanOmiQ platform accelerates Whole Genome Sequencing, enhancing precision medicine with AI-driven genomic analysis.
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  17. Butterfly Network announces $75.6 million public offering to fund product development and commercialization.
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  18. FDA approves Ozempic® to reduce kidney disease and cardiovascular death risk in Type 2 Diabetes with Chronic Kidney Disease.
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  19. Kinectrics and Isotopia partner to supply Gadolinium-160, advancing Terbium-161 radiotherapeutics for prostate and neuroendocrine tumors.
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  20. Quibim secures $50M for US expansion, enhancing AI tools for tumor detection in MRI, CT, and PET scans.
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  21. Tempus acquires Ambry Genetics to enhance AI-driven precision medicine solutions for improved patient care.
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  22. Acellera and Psivant partner to enhance drug discovery using AI and quantum simulations for small molecule therapeutics.
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  23. Pfizer's BRAFTOVI regimen improves survival in Phase 3 trial for metastatic colorectal cancer with BRAF V600E mutation.
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  24. FDA approves Journavx, a first-in-class non-opioid analgesic for moderate to severe acute pain in adults.
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  25. March Biosciences' MB-105 CAR-T therapy receives FDA orphan drug status for T-Cell Lymphoma.
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