February 11, 2025 - 🧬 [nGram] Your Weekly Business Development Insights (4th Feb - 10th Feb): Eli Lilly's Strategic Moves & FDA Approvals


  1. Nuvectis Pharma raises $15.5 million to advance oncology drug candidates NXP800 and NXP900.
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  2. Globus Medical acquires Nevro for $250M to expand in chronic pain management with neuromodulation platforms.
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  3. Aprea Therapeutics strengthens IP portfolio for DNA Damage Response cancer therapeutics, advancing ATR and WEE1 inhibitor programs.
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  4. AdvanCell partners with Lilly to develop targeted alpha therapies for Cancer using Pb-212 technology.
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  5. Immunovant advances IMVT-1402 trials in Graves' Disease and Rheumatoid Arthritis with six INDs cleared.
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  6. Erasmus Medical Center approves Phase 2 trial of Ampligen and Imfinzi for late-stage Pancreatic Neoplasms.
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  7. NEJM publishes eNRGy trial results for BIZENGRI, FDA-approved for NRG1+ Pancreatic Adenocarcinoma and NSCLC.
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  8. Onc.AI's AI model receives FDA Breakthrough Device Designation for improving survival predictions in metastatic non-small cell lung cancer.
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  9. Cure Rare Disease receives $5.69M CIRM grant to advance gene therapy for Spinocerebellar Ataxia Type 3.
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  10. OliX and Lilly partner to develop OLX75016 for Metabolic-Associated Steatohepatitis and cardiometabolic conditions.
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  11. Kura and Kyowa Kirin report positive results for ziftomenib in relapsed/refractory NPM1-mutant acute myeloid leukemia.
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  12. Cumberland's ifetroban improves cardiac function in Duchenne Muscular Dystrophy Phase II trial.
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  13. Zenocutuzumab shows durable efficacy in NRG1 fusion-positive pancreatic adenocarcinoma and NSCLC, published in NEJM.
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  14. CAR T-cell therapy market projected to grow to $15.2 billion by 2035, driven by CD19 and BCMA target antigens.
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  15. IO Biotech publishes preclinical data on IO112, a cancer vaccine targeting Arginase 1, with IND submission expected in 2025.
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  16. SelectQuote secures $350M investment from Bain Capital, Morgan Stanley, and Newlight to expand healthcare services.
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  17. Eli Lilly partners with AdvanCell and OliX to advance radiopharmaceuticals and Metabolic-Associated Steatohepatitis (MASH) treatments.
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  18. Algiax's AP-325 shows promising results in Phase 2a trial for Neuropathic Pain, offering rapid and lasting relief without opioid risks.
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  19. Cusatuzumab leads Phase II trials for Acute Myeloid Leukemia, advancing CD70-targeting therapies in oncology.
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  20. AI discovers new protein compounds effective against bacterial and fungal infections in mice, aiding antimicrobial resistance fight.
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  21. FDA grants priority review to Insmed's Brensocatib for Bronchiectasis, with action date set for August 12, 2025.
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  22. Boehringer's nerandomilast meets primary endpoint in Phase III trial for Progressive Pulmonary Fibrosis.
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  23. MIT project funded to develop algorithms enhancing cerebrospinal fluid flow to combat neurodegeneration in aging.
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  24. FDA approves EMBLAVEO for complicated intra-abdominal infections with limited treatment options.
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  25. Cotiviti to acquire Edifecs, enhancing healthcare data interoperability and value-based care solutions.
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