February 18, 2025 - 🧬 [nGram] Your Weekly Business Development Insights (11th Feb - 17th Feb): Moderna's Vaccine Hold, Pfizer's Prostate Cancer Breakthrough, & More


  1. FDA halts Moderna's norovirus vaccine trial due to a Guillain-Barré syndrome case under investigation.
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  2. 3Z Pharmaceuticals' study reveals amlodipine's potential as a non-stimulant therapy for Attention Deficit Hyperactivity Disorder.
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  3. Gates, Novo Nordisk, and Wellcome launch $50M initiative to combat Antimicrobial Resistance in low- and middle-income countries.
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  4. Innovent's IBI363 gains second FDA Fast Track Designation for Squamous Non-Small Cell Lung Cancer treatment.
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  5. Olympus Partners acquires PAI Pharma, a leader in generic oral liquid medicines, to enhance growth and market presence.
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  6. Pfizer's investigational combo reduces Prostatic Neoplasms progression by 49% in Phase I trial.
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  7. FDA approves Merilog, the first rapid-acting insulin biosimilar, for Diabetes Mellitus treatment, enhancing access to cost-effective insulin options.
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  8. FDA grants Breakthrough Therapy Designation to lacutamab for relapsed or refractory Sézary Syndrome after promising trial results.
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  9. Bristol Myers Squibb's Sotyktu shows consistent safety and efficacy over five years in treating moderate-to-severe plaque psoriasis.
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  10. Volta Medical's AI-guided ablation improves Atrial Fibrillation outcomes, achieving 88% symptom-free rate in a major clinical trial.
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  11. Incyclix Bio's INX-315 shows promise in overcoming resistance to CDK4/6 inhibitors in breast and pancreatic cancers.
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  12. InnoCare's Phase III trial of ICP-248 and orelabrutinib for Chronic Lymphocytic Leukemia approved in China.
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  13. FDA approves GSK's PENMENVY vaccine for Meningococcal Groups A, B, C, W, and Y in individuals aged 10-25 years.
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  14. DAAN Biotherapeutics partners with LigaChem for ADC development targeting solid tumors.
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  15. Terrain Biosciences launches to accelerate RNA therapeutics and vaccine development using AI and proprietary manufacturing, raising $9M in seed funding.
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  16. Bambusa Therapeutics raises $90M to advance bispecific antibodies for Immunology and Inflammation Diseases.
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  17. Exelixis reports sustained efficacy of CABOMETYX and Opdivo in advanced Renal Cell Carcinoma after five years.
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  18. Augustine Therapeutics appoints Gerhard Koenig as CEO to lead clinical-stage transition for HDAC6 inhibitors.
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  19. Foresee Pharmaceuticals' Casppian Phase 3 trial for Central Precocious Puberty receives third positive DSMB safety recommendation.
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  20. Seaport Therapeutics' GlyphTM platform enhances lymphatic drug transport, achieving up to 55% absorption for improved therapeutic exposure.
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  21. Bambusa Therapeutics raises $90M to advance bispecific antibodies for immunological and inflammatory conditions.
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  22. Tenet Healthcare reports strong 2024 results with significant revenue growth and strategic hospital divestitures.
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  23. AbbVie and Xilio partner to develop tumor-activated immunotherapies, leveraging Xilio's proprietary technology for cancer treatment.
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  24. Genomic data market to reach $5.89 billion by 2033, driven by precision medicine and innovative profiling tools.
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  25. Quantum-Si to announce 2024 financial results and business update on March 3, 2025.
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