August 30, 2024 - 🧬 [nGram] Today’s Neurology Scoop: Merck's Phase III Study & Kiyatec's 3D Predict™ Glioma


  1. Merck KGaA announces first patient dosed in phase III study of oral cladribine in generalized myasthenia gravis
    • Merck KGaA has dosed the first patient in the Phase III MyClad trial for oral cladribine in treating generalized myasthenia gravis (gMG).
    • The MyClad trial is a global, randomized, double-blind, placebo-controlled study involving 240 patients.
    • Cladribine capsules aim to selectively target B and T lymphocytes, potentially slowing disease progression and reducing treatment burden.
    • gMG is a rare neuromuscular disorder causing muscle weakness, affecting approximately 700,000 people worldwide.
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  2. Kiyatec announces publication of groundbreaking study on 3D Predict Glioma in high-grade glioma patients
    • Kiyatec's study on the 3D Predict Glioma test was published in Scientific Reports.
    • The test significantly improves progression-free and overall survival in high-grade glioma (HGG) patients.
    • The study enrolled 102 newly diagnosed HGG patients from multiple centers in the U.S.
    • Patients identified as responders had a median progression-free survival increase of 5.8 months and overall survival increase of 7.6 months.
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