January 2, 2025 - 🧬 [nGram] Today’s News Scoop: Neumora's KOASTAL-1 Study on Depression


  1. Neumora Therapeutics reports data from KOASTAL-1 study of navacaprant in major depressive disorder
    • The KOASTAL-1 study did not show statistically significant improvement in depressive symptoms with navacaprant compared to placebo.
    • An efficacy signal was observed in female participants, prompting further analysis by the company.
    • Navacaprant was generally well-tolerated, with a safety profile similar to placebo and no serious adverse events reported.
    • Neumora plans to provide additional updates on the navacaprant development program at the J.P. Morgan Healthcare Conference.
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